Lipitor and lipitor call your lipitor doctor lipitor right lipitor away. For the lipitor lipitor lipitor -treated patients, median (min, max) baseline TG level was 565(267-1502). Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Overdose: If overdose is suspected, contact a lipitor poison control center or emergency room immediately. How to store Lipitor. How do I store lipitor Store lipitor at room temperature, 68 to 77F (20 to 25C). Talk to your doctor about the lipitor benefits and lipitor risks. Patients should be lipitor advised lipitor to report promptly unexplained muscle pain, tenderness, or weakness, particularly if accompanied by malaise or fever or if muscle signs and symptoms persist after discontinuing lipitor. How to take Lipitor Before starting treatment, your doctor will place you on a low-cholesterol diet, which you should maintain lipitor also during therapy with lipitor Lipitor. Grapefruit can increase the lipitor amount of lipitor this lipitor medication in your bloodstream. Check with lipitor your doctor or pharmacist before taking. Reporting of lipitor side effects If you get any side effects, talk to your doctor, pharmacist or nurse. Possible side effects reported with lipitor some statins (medicines of lipitor the same type - canada lipitor Sexual difficulties - Depression - Breathing problems including persistent cough and/or shortness of breath or fever - Diabetes. Your doctor will adapt the dose lipitor at intervals of 4 weeks or more. The reductions in LDL-C from baseline were lipitor generally consistent across age groups within the trial as well as with previous clinical studies lipitor in both adult and pediatric lipitor placebo-controlled trials. The proportions of subjects who lipitor experienced cardiovascular death were numerically smaller in the lipitor80 mg lipitor group (3.3) than in the placebo lipitor group (4.1). Based on observations in rats, lipitor is likely to be secreted in human milk see lipitor contraindications and Use in Specific Populations. The incidence of nonfatal hemorrhagic stroke was significantly higher in the atorvastatin group (38,.6)as compared to the placebo group (16,.7). Lactation Advise women not to breastfeed during treatment with lipitor see contraindications and Use in Specific Populations. In animals, the ortho-hydroxy metabolite undergoes further glucuronidation. UK PIL dated july 201 AND safety warning 27/3/12 date OF proof: 6464/1255 1256B ks code: 04-1957 Atorvastatin lipitor 20mg 40mg tabs artworker: date: Taking other medicines There are some medicines that may lipitor change the effect of Atorvastatin, or their effect may be changed by Atorvastatin. Some products that may interact with this drug include: cyclosporine, gemfibrozil, telaprevir, tipranavir plus ritonavir. There is no available information on the effects of the drug on the breastfed infant or the effects of the drug on milk production. Brain hemorrhage and optic nerve vacuolation were seen in another female dog that was sacrificed in moribund condition after 11 weeks of escalating doses lipitor up to 280 mg/kg/day. Therefore, caution should be applied and the lowest dose lipitor lipitor necessary should be used. HOW lipitor supplied Dosage Forms And Strengths lipitor tablets are white elliptical, film-coated, and are available in four strengths (see Table 1). You should consult your doctor as soon as possible. General population, the estimated background risk lipitor of major lipitor birth defects and miscarriage in clinically recognized pregnancies is 2-, respectively. In the lipitor placebo-controlled clinical trial database of 16,066patients (8755 lipitor. This product is available in all of the above names and strengths, but will be referred to throughout this leaflet as Atorvastatin. Collaborative Atorvastatin Diabetes Study (cards) In cards see Clinical Studies involving 2,838 subjects (age range 39-77 years, 32 lipitor women;.3 Caucasians,.4 South Asians,.3 Afro-Caribbean,.0 other) with type 2 diabetes treated with lipitor 10 mg daily(n1,428). It is very important to continue to follow your doctor's advice about diet and exercise. In this double-blind, placebo-controlled study, patients were treated with anti-hypertensive therapy (Goal BP 140/90 mmHg for non-diabetic patients; 130/80 mmHg for diabetic patients) and allocated to either lipitor10mg daily (n5168) or placebo (n5137 using a covariate adaptive method which. Treatment with lipitor80mg/day significantly reduced the rate of mcve(434 events in the 80 mg/day group. Due to the small number of events, results for women were inconclusive. HOW TO store lipitor Keep this medicine out of the sight and reach of children. Diabetes was reported as an adverse reaction in 144 subjects (6.1) in the atorvastatin group and 89 subjects (3.8) in the placebo group see warnings AND precautions. 374(8.4)in the simvastatin 20- 40 mg /day group. Table 11: Lipid-altering Effects of lipitor in Adolescent Boys and Girls with Heterozygous Familial Hypercholesterolemia or Severe Hypercholesterolemia(Mean Percentage Change From Baseline at Endpoint in Intention-to-Treat lipitor generic lipitor Population) dosagotal-C LDL-C HDL-C TG Apolipoprotein B Placebo 47 -1.5 -0.4 -1.9. Passing brown lipitor or dark-colored urine. The safety of Atorvastatin during pregnancy and breast-feeding has not yet been proven. Drug interactions may change how your medications work or increase your risk for serious side effects. Elevated blood sugar levels have been reported with statins, including. Approved: customer approved: proof history:.1 - waymade - 21/02/12.2 - waymade - 27/3/12 Very rare: affect less than 1 user in 10,000: If you experience problems with unexpected or unusual bleeding or bruising, lipitor this may be suggestive of a liver complaint. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially lipitor of the face/ tongue /throat severe dizziness, trouble breathing. However, try to take your tablet at the same time lipitor every day. Adverse reactions associated with lipitor therapy reported since market introduction, that are notlisted above, regardless of causality assessment, include the following: anaphylaxis, angioneurotic edema, bullous rashes (including erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis rhabdomyolysis, myositis, fatigue, tendon rupture, fatal. The risk of this occurring is increased when taking certain types lipitor of medication or consuming lipitor larger quantities ( 1liter) of grapefruit juice. 40 mg of atorvastatin PD 157 on one side and 40 on the other 80 mg of atorvastatin PD 158 on one side and 80 on the other Storage And Handling 10 mg tablets (10. However, do not drive if this medicine affects your ability to drive. If you notice any of the following rare but serious side effects, tell your doctor right away: yellowing eyes / skin, dark urine, severe stomach / abdominal pain, persistent nausea / vomiting. This medication may rarely cause liver problems. One patient in clinical trials developed jaundice. The long-term efficacy of lipitor therapy in childhood to reduce morbidity and mortality in adulthood has not been established. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Talk to your healthcare lipitor provider if you have side effects that bother you or that will not go away. Breastfeeding while taking Lipitor is not recommended. 548eventsin lipitor the 10 mg/day group) with a relative risk reduction of 22, HR0.78,95CI(0.69,.89.0002(see Figure 3 and Table6). Precautions Skeletal Muscle Rare cases of rhabdomyolysis with acute renal failure lipitor secondary to myoglobinuria have been reported with lipitor and with other drugs in this class. In animal reproduction studies in rats and rabbits there was no evidence of embryo-fetal toxicity or congenital malformation sat doses up to 30 and 20 times, respectively, the human exposure at the maximum recommended human dose (mrhd)of 80 mg, based on body surface area (mg/m). Atorvastatin was negativein the in vivo mouse micronucleus test. What lipitor IS AND what IT lipitor IS used FOR Lipitor belongs to a group of medicines known as statins, which are lipid (fat) regulating medicines. The low systemic availability is attributed to presystemic clearance in gastrointestinal mucosa and/or hepatic first-pass lipitor metabolism. Lipitormay harm your unborn baby. Lipitor is for adults and children over 10 whose cholesterol does not come down enough with exercise and a low-fat diet alone. Additionally, analysis of the pooled data demonstrated consistent and significant decreases in total-C, LDL-C, TG, total-C/HDL-C, and LDL-C/HDL-C. In rare cases, atorvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, lipitor leading to kidney failure. There have been rare post marketing reports of fatal and non-fatal hepatic failure in patients taking statins, including atorvastatin. This is more likely if you have high levels of sugars and fats in your blood, are overweight and have high blood pressure. Lipitor significantly reduced the rate of major cardiovascular events (primary endpoint events) (83 events in the lipitor group. Take this medication regularly in order to get the most benefit from. Do not use after the last day of the month shown in the expiry date on the carton and blister. In Canada - Call your doctor for medical advice about side effects. A very serious allergic reaction to this drug is rare. Lipitor significantly decreased plasma levels of total-C, LDL-C, triglycerides, and apolipoprotein B during the 26-week double-blind phase (see Table 11). It lowers the LDL -C (bad cholesterol) and triglycerides in your blood. You may report side effects to Health Canada. Contents of the pack and other information. Therefore, in patients taking itraconazole, caution should be used when the lipitor dose exceeds 20 mg see dosage AND administration and warnings AND precautions. Limited published data on the use of atorvastatin are insufficient to determine a drug-associated risk of major congenital malformations or miscarriage. Male rats given 100 mg/kg/day for 11 weeks prior to mating had decreased sperm motility, spermatid head concentration, and increased abnormal sperm. Lipitor and during your treatment if you have symptoms of liver problems. Do not take this medicine after the expiry date shown on the carton or blister pack. Ritonavir, lopinavir, atazanavir, indinavir, darunavir, etc. Tell your doctor about all your medical conditions and all medications you take. 463 (10.4) in the simvastatin 20- 40 mg /day group,.89, 95 CI (.78,.01.07. The reduction in the rate of CHF with hospitalization was only lipitor observed in the 8 of patients with a prior history of CHF. It is important to continue taking this medication even if you feel well. NDC bottles of bottles of x 10 unit dose blisters NDC bottles of 1000 20 mg tablets (20 mg of atorvastatin coded PD 156 on one side and 20 on the other. Prescription required, important: HOW TO USE this information: This is a summary and does NOT have all possible information about this product. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, alcohol use. Patients takingdigoxin should be monitored appropriately. Caution should be exercised if a statin is administered concomitantly with drugs that may decrease the levels or activity of endogenous steroidhormones, such as ketoconazole, spironolactone, and cimetidine. Do not take Atorvastatin if you are breast-feeding. A 2-year carcinogenicity studyin mice given 100,200, or 400 mg/kg/day resulted side effects of lipitor in a significant increase in liver adenomas in high-dose males and liver carcinomas in high-dose females.
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